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Although there are many ongoing large CVD outcome trials of GLP-1 RA treatment (Table 1), more simultaneous investigation of the causal relationship between GLP-1 RA administration and useful surrogate measures of CVD, including carotid IMT, would help us understand the potential mechanisms through which GLP-1 RAs may result in favorable cardiovascular outcomes in patients with T2D

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Yes, all of these are subcutaneous injectable medications Patients self-administer the injections, typically once daily (Saxenda) or once weekly (Wegovy, Ozempic, Zepbound) A pharmacist or healthcare provider will teach proper injection technique Dose adjustments should not be done independently

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Its a single molecule